These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease. © Copyright 2012. IBSAid® is a registered trademark.

Mechanisms of Action
IBS Aid is a unique and proprietary product which
contains a rich dietary source of nucleotides.
Nucleotides are the building blocks of DNA and RNA,
which are needed by the body in very large quantities
to produce the millions of cells it needs every day to
carry on all of its metabolic, disease fighting, growth,
repair and health maintenance functions. Studies indicate
that the supplemental consumption of concentrated
nucleotides, such as those found in IBS Aid, is useful in
relieving symptoms of IBS.
 
The primary reason for the relief of symptoms when using IBS Aid is that it addresses the causes of IBS by virtue of making positive changes in intestinal villi and mucosa in your intestines. It additionally results in changes in microflora with an increase of beneficial bacteria, such as Lactobacilli, and a reduction of the “bad” E. coli bacteria.  Numerous animal studies have repeatedly verified these findings (see microscopic photographs below), and two human clinical trials have supported these conclusions as well. There is also an abundance of anecdotal evidence and personal testimonials, as our product is also being sold in Europe and Asia.
                                
In studies done at universities and commercial laboratories, IBS Aid was shown to substantially reduce or eliminate many to all of the symptoms related to gastrointestinal distress, such as chronic diarrhea, frequent urgency, painful cramps, incomplete bowel evacuation, bloating, fatigue, weakness, malaise and weight loss.
 
Clinical research completed in 2003 at the University of Guelph in Ontario, Canada, demonstrated the effectiveness of the IBS Aid formula in reducing or eliminating many to most of these common symptoms associated with IBS. The study reached the following conclusion:
“The administration of IBS Aid decreased straining, hard stool and incomplete evacuation in individuals with IBS without causing any adverse effects. In addition, IBS Aid reduced the number of days with reported straining, flatulence and incomplete evacuation. The above improvements were generally observed after 4-6 weeks of treatment. The product also tended to improve almost all other symptoms of IBS, especially mucus and urgency.”
 
The findings of this study resulted in a large scale government funded clinical trial at the University of East London in the UK which was recently completed and verified the results from the study in Canada.
 
Understanding Nucleotides
 

Deoxyribonucleic acid, DNA, which makes up the genetic material in cells, is comprised of units called nucleotides. A nucleotide consists of a base, a sugar and a phosphate group. These nucleotides are Adenosine (A), Guanosine (G), Cytidine (C) and Thymidine (T). Uridine (U) is a fifth nucleotide, which is used to make RNA, (ribonucleic acid) along with A, G, and C.

Nucleotides are most recognized as the building blocks of DNA and RNA. They are, by themselves, or in combination with other molecules, involved in almost all the activities of the cell, including metabolism, transfer of energy and mediation of hormone signals.

 

Nucleotides are directly linked to

protein synthesis and tissue repair.


The living body has an on-going demand for new cell production, and must create cells at a rate as fast as the speed at which its cells die. To do this, a typical cell must double its mass and all of its contents in order to produce two new "daughter" cells. This multiplication of a cell starts with the doubling of its genetic information contained in its DNA. This is called interphase. A normal strand of DNA consists of over three billion nucleotides.

After the DNA has duplicated, the M-Phase begins, during which two cell nuclei are formed and the cell divides into two new separate and identical ones. Providing dietary sources of nucleotides has been shown to accelerate multiplication of certain cells.

  • Both the maintenance and growth of our biological systems require proliferation of many types of cells.
  • Cell proliferation is a lengthy and complicated process dependent on energy and the continuous supply of its specific nucleotide building blocks.
  • Nucleic acids are essential to immune function and regenerating bodily tissues
                            
 
It was thought that the body could synthesize a sufficient number of nucleotides from smaller precursor molecules, and, thereby, meet its need via "de novo" synthesis or dead cell recycling. However, extensive research over the last decade, indicates that this may not be correct. Instead, it is now known that the body requires dietary nucleotides to meet all of its physiological requirements.

Under conditions of rapid growth, limited food supply, metabolic stress and disease, the body's demand for nucleotides exceeds that of de novo synthesis. Dietary nucleotides, nucleosides and nucleic acids become essential nutrients under these conditions and will supplement the metabolically-taxing method of de novo synthesis.

Dietary nucleic acids are found in food at different concentrations. The dietary intake of RNA is typically about one order of magnitude greater than DNA, and is particularly present in foods such as liver, tripe, yeast extracts, fungi, lean meat and fish.

Interestingly, mother's milk is a rich source of nucleic acids, especially RNA and nucleotides. Research conducted in infant nutrition has led to an increasing number of infant formulas with supplemented nucleotides. More recent adult research has led to some dietary supplements containing specific, pure and concentrated formulas of all five nucleotides. These are products used to accelerate and intensify natural immune response and to relieve intestinal distress and disorders through repair.
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